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N-alpha-Acetylcarnosine is proposed for treatment of ocular disorders that have a component of oxidative stress in their genesis
Nalpha-acetylcarnosine is proposed as a prodrug of L-carnosine that is resistant to enzymatic hydrolysis by carnosinase with ability to give ...
Oxidative stress in the human trabecular meshwork clinically correlated with primary open-angle glaucoma
Study evaluated intensity of oxidative molecular damage and its clinical correlation to intraocular pressure. It found that oxidative stress could ...
The role of free radical-induced lipid oxidation in the development of cataracts in human and canine eyes
Free radical-induced lipid oxidation causes accumulation of lenticular lipid peroxidation (LPO) products. Lens opacity correlates with the level of the ...
Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants
The authors present strong evidence that mitochondrial complex I defects are the major source of oxidative stress in TM cells ...
Protective effects of melatonin in experimental free radical-related ocular diseases
Current evidence suggests that melatonin may act as a protective agent in ocular conditions such as photo-keratitis, cataract, glaucoma and ...
Melatonin in the eye: implications for glaucoma
Melatonin, being an efficient antioxidant with antinitridergic properties, has a promising role in the treatment and management of glaucoma.