The role of free radical-induced lipid oxidation in the development of cataracts in human and canine eyes
Free radical-induced lipid oxidation causes accumulation of lenticular lipid peroxidation (LPO) products. Lens opacity correlates with the level of the LPO accumulation. Oxidation of lens proteins is due to a decreased glutathione concentration in the lens.
Treatment with 1% N-acetylcarnosine (NAC) protects telomeres to prevent and dissolve mature cataracts in dogs.
Cataracts in small animals are caused by oxidative stress on lens epithelial cells. Treatment with 1% N-acetylcarnosine (NAC) releases L-carnosine ophthalmically, stabilizing telomeres to help prevent and dissolve mature cataracts in dogs.
N-alpha-Acetylcarnosine is proposed for treatment of ocular disorders that have a component of oxidative stress in their genesis
Nalpha-acetylcarnosine is proposed as a prodrug of L-carnosine that is resistant to enzymatic hydrolysis by carnosinase with ability to give efficient protection against oxidative stress both in the lipid phase of biological membranes and in aqueous environments.
In study 90.0% of the eyes treated with N-acetylcarnosine, 1% sol (NAC) showed a gradual improvement in b/c VA to 7-100%
Statistical analysis revealed the significant differences over 6 and 24 months in cumulative positive changes of overall characteristics of cataracts in the NAC-treated Group II from the control Group I.
In clinical test NAC-treated eyes had statistically significant difference in VA, glare sensitivity compared to control at 4-months
1% N-acetylcarnosine (NAC) eye drops were applied topically to the eyes of older drivers. Study results provide a substantial basis for further evaluation of NAC in the treatment and prevention of vision impairment …
Animal Clinical Trials Prove Can-C™ Safe and Effective “A new phenomenon of “melting snow” in only a few short weeks…
The testing of various anti-glycation agents over nearly a decade led a Russian research team to the development of n-alpha-acetylcarnosine as a delivery system for the natural eye anti-oxidant of L-carnosine.
Researchers found the healthy eye contains high levels of the natural antioxidant carnosine. Interestingly the eyes of those suffering from degenerative ocular diseases such as cataracts were found to be grossly deficient in this essential ocular antioxidant.
Study results showed an effective rate of 100% on primary senile cataract (i.e. all patients experienced an improvement). For those with cataracts the longest, in some cases more than 20-years, the effective rate was still an extremely impressive 80%.
Animal Clinical Trials Prove Can-C™ Safe and Effective “A new phenomenon of “melting snow” in 96% of canines in only a few weeks…
These studies produced remarkably fast results in the improvement of clarity, glare sensitivity and overall vision for the animals involved. Furthermore, no serious side effects were noted and the beneficial affects were sustainable.