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Glaucoma Programs

damage to the optic nerve

Glaucoma is a group of eye conditions that damage the optic nerve, the health of which is vital for good vision. This damage is often caused by an abnormally high pressure in your eye. Glaucoma is one of the leading causes of blindness for people over the age of 60.

Glaucoma Standard Program

6 week supply

Standard Program

Glaucoma Standard Program

$104.95 or $99.70 every 6 weeks

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BENEFITS OF THE PROGRAM

  • Healthy eyes contain high levels of the natural antioxidant L-Carnosine. Interestingly, the eyes of those suffering from degenerative ocular diseases such as Glaucoma were found to be highly deficient in L-Carnosine. Can-C™ Eye Drops help counter oxidative stress on the eyes and provide targeted support for those who suffer from Glaucoma.
  • The prime ingredient in Can-C™ is a proprietary form of N-Acetyl-Carnosine (NAC), which acts as both a stabilizer and carrier for L-Carnosine, safely delivering it into the fluid area of the eye surrounding the lens, allowing Carnosine to access the areas it needs to in order to act as a natural and highly effective antioxidant that protects and heals the eye from Glaucoma and other ocular disease.
  • Years of research went into identifying the right purity level of N-Acetyl-Carnosine (NAC) to ensure safety as well as optimal results. This purity level is proprietary to our Can-C™ N-Acetyl-Carnosine Eye Drops, so look for the approved Can-C™ hologram on the box of any Can-C™ eye drop product prior to applying to the eyes.
  • Nac-C Plus™ Capsules enhance the effectiveness and duration of Can-C™ Eye Drops’ activity in the eye, thereby speeding up the healing response. In addition, Nac-C Plus™ Capsules reduce oxidation in the eyes and may facilitate a healing response in the eyes of Glaucoma patients.
  • Nac-C Plus™ Capsules work together with Can-C™ Eye Drops to support and speed up the healing process by keeping the lens of the eye safe from degradation, delivering essential nutrients, enhancing DNA repair, and reducing oxidative stress that could otherwise inhibit the natural healing process. These capsules include natural vitamins, minerals, antioxidants, and amino acids that have been clinically proven to help improve eye health and fight common eye disease like Glaucoma.
  • Ingredients in Nac-C Plus™ Capsules like N-Acetyl-Cysteine, L-Histidine, and L-Carnosine have been show to work synergistically to improve vision by increasing glutathione levels and acting as antioxidants to spare the lens of the eye from oxidative stress, keeping it flexible and clear. Vitamin E and Zinc can also decrease risk of Glaucoma and other age-related eye disease.

Glaucoma Advanced Program

2 months supply

Advanced Program

Glaucoma Advanced Program

$242.39 or $230.27 every 2 months

With Nac-C Plus™ for enhanced support

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BENEFITS OF THE PROGRAM

  • Same benefits as Standard Program PLUS:
  • Contains a unique Melatonin, from organic, pharmaceutical-grade, plant-based ingredients, bonded with Selenium and Zinc. It acts as an efficient antioxidant and protects the tissues of the eye against cataract formation. Melatonin also helps regulate immunological hormone functions to ensure optimal eye healing and repair.
  • Improves the body’s natural and optimal night-peak release of Melatonin. This bonded melatonin formula, when taken nightly, was found to re-establish optimal circadian rhythms, resulting in healing and repair response in the eyes, as well as protecting the retinal epithelium (RPE) from oxidative damage.
  • Melatonin provides powerful antioxidant protection for the eyes, and clinical studies have shown that it may have a promising role in the safe treatment and management of Glaucoma.
  • These 3 products together form a powerful triad for ocular healing and repair.

A higher (loading) dose of Can-C™ Eye Drops is recommended in the first few months of use to quickly re-establish optimal N-Acetyl-Carnosine (NAC) levels in the eyes; two drops applied in the morning to each eye (4 drops total) and two drops in the evening to each eye (4 drops total). The quicker these levels can be elevated in your eyes the sooner you will begin to see visual improvements. This initial (loading dosing period) lasts anywhere from 3 to 6 months depending upon the severity of your eye condition.

Once you begin to see notable improvements in brightness and clarity you may be confident that you have effectively re-established optimal NAC levels in your eyes, but the improvements don’t stop there. The good news is that once the NAC levels have been re-established to optimal levels in the eyes it is very easy to keep them there at half the cost. After three to six months of consistent use, only half the recommended Can-C dose is needed to effectively maintain these new levels, and the vision improvements will continue.

While many report visual improvements in as little as three months’ time, generally the most dramatic improvements will be reached between six and twelve months of consistent use. Once optimal results have been achieved, the maintenance dose of only one to two drops daily will prevent the return of the Cataracts and continue to support and improve the health of your eyes.

The benefits of Can-C™ are long-lasting, however if the drops are discontinued, the same deficiency that allowed the ocular condition to form in the first place will likely return again. Fortunately, by simply using a minimal amount of the product consistently, the good results can be maintained at less than half the initial cost.

Can-C™ eye drops initial loading dose: two drops applied in the morning to each eye (4 drops total) and two drops in the evening to each eye (4 drops total).

Can-C™ eye drops maintenance dose (general eye health support and prevention): After 3 to 6 months of use you will only need to use 1-2 drops of Can-C™ in each eye daily, with a one week pause from use every two months. The product will last a very long time at this level of usage.

Nac-C Plus™ Capsules dose: take 2 capsules daily Nac-C Plus™ Capsules. When used in conjunction with Can-C™ eye drops, Nac-C Plus capsules increase the length of time that Can-C™ eye drops stay active in the eye by inhibiting the breakdown of the L-carnosine that has been topically administered through the drops. This sustained effect significantly enhances free radical protection and decreases the oxidative environment within the eye, allowing for a faster healing response.

Advanced Program Protocol
ARMeD Capsules dose: Take 1 tablet before bedtime, ideally between 10PM and 11PM.

Independent clinical results are based on consistent daily use.

Approximately 15 million people in the United States suffer from Age-Related Macular Degeneration (AMD), and more than 1.7 million Americans have the advanced form of the disease. It is the most common cause of vision loss among the aging population.

While there’s no medical “cure” for AMD, current research has revealed that specific nutrients could help prevent and even reverse the progression of AMD, preserving the vision of millions of aging individuals.

What is AMD?

AMD stands for Age-Related Macular Degeneration, and it is an eye disease that is common in older individuals. It causes central vision loss due to damage to a part of the retina called the “macula.”

Dry Macular Degeneration, the most common type of AMD, involves a deterioration of the center of the retina that progresses slowly over many years and is treatable with supplementation as well as other methods. Wet Macular Degeneration, meanwhile, is caused by leaky blood vessels growing under the retina; it has a much faster onset and can cause a relatively sudden loss of vision, requiring immediate medical attention and likely surgery or laser treatment.

What are the symptoms of AMD?

AMD is characterized by a gradual loss of central vision, which can express itself as blurry or reduced quality image in the center of your vision. If left untreated, it can progress to even greater central vision loss. While not total blindness, the loss of central vision does lead to a blind spot in the center that affects the ability to see fine details and complete tasks that involve reading.

Dry Macular Degeneration symptoms typically develop slowly and painlessly. They can include:

  • A blurry spot or blind spot within your field of vision
  • Reduced vision in the center of one or both eyes
  • Difficulty adapting to low light environments like a dimly lit restaurant
  • Needing to use brighter light than usual to see what you’re reading or working on
  • Printed text looks blurry
  • Colors look more dull than usual
  • Trouble with facial recognition

AMD can affect one or both eyes. If just one eye is affected, it may be hard to observe any changes to your vision due to your good eye compensating for the weak eye. Since AMD doesn’t affect peripheral vision, it rarely causes total blindness.

What causes AMD / Am I at risk for AMD?

AMD is caused by damage over time to a part of the retina called the “macula,” which is why it is most common in aging adults and the elderly. Despite its slow onset, AMD is the leading cause of vision loss among those over 60.

Factors that may increase your risk of macular degeneration include:

  • Age: AMD typically develops in individuals over 60.
  • Family History / Genetics: AMD can be hereditary. Researchers have identified several genes related to developing Macular Degeneration.
  • Diet: Eating foods that are rich in antioxidants, like blueberries or kale, can help your eyes defend against the oxidative damage that causes vision loss.
  • Smoking: Smoking or being exposed to cigarette smoke on a regular basis can significantly increase your risk of AMD.
  • BMI: Research has shown that obesity may increase the likelihood of early Macular Degeneration progressing to a more severe version of AMD.
  • Ethnicity: Macular Degeneration is most common in Caucasians.
  • Cardiovascular Health: People who have had diseases that affected their heart and/or blood vessels may be at higher risk of developing macular degeneration.

How can I lower my risk for AMD?

  1. Eat a nutritious and healthy diet – AMD develops due to oxidative damage over time. Eating a diet high in antioxidant-rich foods like berries and colorful vegetables can be an effective way to give your body the tools to fight off age-related eye disease and the vision loss it causes. Fruits (like strawberries & pomegranates) and green leafy vegetables (like spinach, broccoli & kale), that are abundant in antioxidants, vitamins A, B, C & E and minerals like calcium, magnesium & zinc, as well vegetables that are rich in carotenoids (like carrots), may have beneficial effects on eye health. A healthy lifestyle and a well-balanced diet have been demonstrated to benefit vision health and may even prevent the progression of eye diseases like AMD.
  2. Maintain a healthy weight – Obesity has been shown to be correlated with AMD progressing to the more advanced form of the disease. It is unclear whether that is because of carrying extra body fat, or if the correlation is caused by the diets of obese people being likely to contain fewer fruits and vegetables that contain the vitamins, minerals, and antioxidants that help fight AMD.
  3. Avoid smoking – Avoiding cigarette smoke can be beneficial for eye health. Smoking was found to be linked to the development of multiple eye diseases, with greater incidence among heavy smokers. Smoking has been shown to reduce corneal thickness, increase eye inflammation, limit tissue oxygen, and release free radicals that cause damage to the eye.
  4. Wear sunglasses – You can protect your retinas from bright light with UV-filtering sunglasses that minimize damage. Try to find a pair of sunglasses that are designed specifically to protect your eyes from UV rays; the best ones will be rated UV400 or higher, meaning that they’ll block 99.9% of UV rays.
  5. Get a regular eye exam – A Dilated Eye Exam is quick, easy, painless, and helps your eye doctor see any initial indications of disease that may exist. It’s a good idea to schedule yearly exams to identify any potential problems early, when treatments are most effective.
  6. Micronutrient Supplementation – You can utilize specialized Can-C™ eye drops, which are designed to support eye health by delivering antioxidants like L-Carnosine to the places in the eye where they’re needed most, reducing oxidative damage that can cause vision loss. There are also supplements full of vision-supporting vitamins and antioxidants that help keep your eyes healthy like ARMeD™ and Nac-C™ Plus Capsules.

What are the treatment options?

While there is no cure for AMD, there are medical treatments that can help slow down the progression of AMD before you lose too much of your vision

Allopathic Treatment options for Wet Macular Degeneration include specialized drugs, laser therapy, and surgery however the success rate is less than satisfactory. Ophthalmologist’s themselves are frustrated with the limitations of effective treatment options for this dreaded condition.

For Dry Macular Degeneration (the most common form of AMD), there aren’t many medical treatment options available. The only recommended treatment options are lifestyle changes, like a diet rich in colorful fruits & veggies and not smoking, or over-the-counter solutions like medicated eye drops and supplements (which include specific vitamins, minerals, and antioxidants such as Vitamin E, Zinc, Selenium, and L-Carnosine).

How effective is supplementation for AMD?

Certain vitamins, minerals, and antioxidants have been shown to be effective for AMD treatment and prevention. Much in the way that eating foods rich in these nutrients can help improve eye health, supplementation can lead to even more targeted results.

In a breakthrough study – Effects of melatonin in age-related macular-degeneration (Yi C, Pan X, Yan H, Guo M, Pierpaoli W. Ann N Y Acad Sci. 2005 Dec;1057:384-92), Dr. Yi Chang, an expert in retinal research, discovered that patients with both dry and wet forms of Macular Degeneration exhibited dangerously low levels of natural melatonin production. He explained that Melatonin is synthesized by the retina before being utilized by the rest of the body. Additionally, it was stated that the only time the Macula heals and repairs itself is during the deep REM state of sleep. His published study with Dr. Walter Pierpaoli revealed that by re-establishing proper melatonin levels the retina was able to effectively heal and repair itself.

His research resulted in the development of an exclusive retinal support formulation called ARMeD™

Wise Choice Medicine’s ARMeD™ Advanced Retinal Support supplement was designed specifically to support and restore optimal retinal health with AMD in mind. Composed of a unique organic Melatonin that is bonded with Selenium and Zinc, it effectively promotes healing and repair, protecting the eye from the damage caused by AMD and other common eye diseases.

How does ARMeD™ work to promote optimal eye healing and repair?

• ARMeD™ contains a unique Melatonin from organic, pharmaceutical-grade, plant-based ingredients, bonded with Selenium and Zinc. It acts as a powerful antioxidant and protects the tissues of the eye. Melatonin also helps regulate immunological hormone functions to ensure optimal eye healing and repair.

• ARMeD™ facilitates the body’s natural healing process by improving the body’s natural and optimal night-peak release of Melatonin. This bonded melatonin formula, when taken nightly, was found to re-establish optimal circadian rhythms, resulting in healing and repair response in the eyes, as well as protecting the retinal epithelium (RPE) from oxidative damage.

• Melatonin controls eye pigmentation, which regulates the amount of UV light reaching the photoreceptors of the eyes. The macular pigment contributes to the protection of the retinal cells from free radicals caused by stress and the sun’s UV radiation.

Wise Choice Medicine AMD Programs

Our Macular Degeneration Standard Program provides a 6-month supply of ARMeD™ for long-term protection from the risk of vision loss. Our Advanced Macular Degeneration Program includes Can-C™ Eye Drops and Nac-C™ Plus Capsules and when combined with ARMeD form a powerful triad of ocular nutrients for those with more advanced AMD or with multiple eye conditions.

Healthy eyes contain high levels of the natural antioxidant L-Carnosine. Interestingly, the eyes of those suffering from degenerative ocular diseases such as Macular Degeneration were found to be highly deficient in L-Carnosine. Can-C™ Eye Drops provide the eye with L-Carnosine, acting as a natural and highly effective antioxidant that protects and heals the eye to provide targeted support for those who suffer from Macular Degeneration.

Nac-C™ Plus Capsules enhance the effectiveness and duration of Can-C™ Eye Drops’ activity in the eye, thereby speeding up the healing response and reducing oxidation in the eyes. These capsules include specific antioxidants, and amino acids that have been clinically proven to target retinal health and facilitate a healing response in the eyes of Macular Degeneration patients.

Macular Degen. Standard Program

Standard Program

6 month supply

Comprehensive program for accelerated results

$100.47 one-time or
$95.45 every 6 months

Macular Degenerat. Advanced Program

Advanced Program

1.5 month supply

Comprehensive program for accelerated results

$105.70 one-time or
$100.42 every 6 weeks

CLINICAL STUDY

Role of melatonin in the eye and ocular dysfunctions

Study: Role of melatonin in the eye and ocular dysfunctions
Publication: Visual Neuroscience , Volume 23 , Issue 6 , November 2006 , pp. 853 – 862
Date published: February 2, 2022
Authors: Per O Lundmark, Seithikurippu R Pandi-Perumal, Venkataramanujan Srinivasan, Daniel P Cardinali
Summary: Melatonin is a ubiquitous molecule and widely distributed in nature, with functional activity occurring in unicellular organisms, plants, fungi, and animals. Several studies have indicated that melatonin synthesis occurs in the retina of most vertebrates, including mammals. The retinal biosynthesis of melatonin and the mechanisms involved in the regulation of this process have been extensively studied. Circadian clocks located in the photoreceptors and retinal neurons regulate melatonin synthesis in the eye. Photoreceptors, dopaminergic amacrine neurons, and horizontal cells of the retina, corneal epithelium, stroma endothelium, and the sclera all have melatonin receptors, indicating a widespread ocular function for melatonin. In addition, melatonin is an effective antioxidant which scavenges free radicals and up-regulates several antioxidant enzymes. It also has a strong antiapoptotic signaling function, an effect that it exerts even during ischemia. Melatonin cytoprotective properties may have practical implications in the treatment of ocular diseases, like glaucoma and age-related macular degeneration.
“Melatonin is an effective antioxidant which scavenges free radicals and up-regulates several antioxidant enzymes. Melatonin cytoprotective properties may have practical implications in the treatment of ocular diseases, like glaucoma and age-related macular degeneration”

CLINICAL STUDY

Melatonin Metabolites Protect Human Retinal Pigment Epithelial Cells from Death Caused by Oxidative Stress

Study: Melatonin Metabolites Protect Human Retinal Pigment Epithelial Cells from Death Caused by Oxidative Stress
Publication: November 2021Pharmaceutical Chemistry Journal 55(8)
Date published: February 2, 2022
Authors: Uras Ebru, Kilicaslan Derya, Kurt Akif Hakan, Alli Bilge and Doðaner Adem
Summary: This study was aimed to determine the efficacy of 6-hydroxy melatonin and N-acetyl serotoninin protecting human retinal pigment epithelial cells from death brought about by oxidative-stress. The ARPE-19 cells (one of the retinal pigment epithelial cell lines) were used as the test cell culture. Following the application of 500 μM H2O2, ARPE-19 cell line culture was incubated for 20 h to induce oxidative stress damage. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide) assay was used to evaluate the oxidative injury to ARPE-19 cells caused by H2O2 and the effectiveness of 6-hydroxy melatonin and N-acetyl serotonin application in preventing this damage. The results indicated that 6-hydroxy melatonin and N-acetyl serotonin exhibited a therapeutic effect on cells damaged by exposure to oxidative stress. It was concluded that these melatonin metabolites might be useful in treating many retinal conditions linked to the oxidative stress-induced damage. In addition, this study proposed a new idea for developing chemical approaches to the design and synthesis/semisynthesis of new drugs.
“It was concluded that these melatonin metabolites might be useful in treating many retinal conditions linked to the oxidative stress-induced damage.”