The Science Behind the Ingredients

ARMeD™ Advanced Retinal Support formula is based on published research conducted by Changxian Yi et al, – titled “Effects of melatonin in age-related macular degeneration”, Ann NY Acad Sci, 1057:384-392,2005 with assistance from the world renowned endocrine specialist and melatonin expert, Dr. Walter Pierpaoli.

Dr. Changxian Yi’s theory was that a specific combination of melatonin, selenium and zinc would have the capacity to control eye pigmentation and thereby regulate the amount of light reaching the photoreceptors in the eye. The unique nutrient combination in the tablets would also scavenge hydroxyradicals and help to protect retinal pigment epithelium cells from oxidative/free radical damage which is considered to be a precursor to ARMD.

For the trial participants, who continued past 6 months onto 12-months of nightly use, the changes in their fundus pictures were remarkable. [Learn More]

ARMeD™ combines, in a unique synergistic formula, three fundamental anti-aging molecules, where melatonin ultimately plays the master role for reactivation and restoration of our circadian rhythm to juvenile levels, resulting in normalization of all measurable immunological and endocrine functions. The age-postponing, metabolic and immunological effects of ARMeD™ can be easily measured by means of a normal periodic check-up.

The ARMeD™ formula contains a unique melatonin from organic, pharmaceutical grade, plant based, ingredients bonded with selenium and zinc. To ensure optimal healing and repair responses, critical excipients work with the bonded melatonin to regulate fundamental immunological hormone functions to a much greater degree.

Please note that ARMeD™ is quite distinct from the sublingual and time-released versions of melatonin supplements in the market place which have a pre-set time of melatonin release. ARMeD™ with bonded melatonin actually mimics nature by improving upon the body’s natural and optimal night peak release of melatonin and the results of this superior action speak for themselves. Take one tablet, each night, before bed time.


According to clinical studies, Melatonin, being an efficient antioxidant with antinitridergic properties, has a promising role in the treatment and management of glaucoma. These same potent antioxidant properties could also protect the tissues of the eye against Age-Related Macular Degeneration, Cataracts, and other disorders.(1)

  1. Per O Lundmark, S R Pandi-Perumal, et al. Melatonin in the Eye: Implications for Glaucoma. Exp Eye Res. 2007 Jun;84(6):1021-30.

Zinc is vital to keeping your eyes healthy and vision sharp. Zinc is concentrated in a part of the retina called the “macula” and helps Vitamin A produce melanin, a pigment which has a protective effect on the eye. A deficiency in zinc has been associated with reduced night vision, while supplementation with zinc has been shown to slow the rate of age-related macular degeneration due to its importance in maintaining a healthy macula.(1) Zinc has also been shown to reduce cataracts by as much as 36% in people ages 65-74.(2)

Research has shown that zinc can correct age-related immuno-depression and several other hormonal and metabolic changes. It has been found that the low zinc levels in aging animals can be restored to normal values with either nocturnal administration of melatonin or transplantation of the pineal gland from young into older animals. Zinc is an essential component of more than 200 enzymes and one of the most relevant trace elements in the body. It is thus clear that additional zinc must be supplemented daily, in order that melatonin can better exert its anti-aging activities on the entire hormonal and immune systems! This important and novel scientific observation of the powerful anti-aging and immuno-enhancing activity of the combination of zinc and melatonin has contributed to the development of ARMeD™ which was proven effective in the clinical trials.

  1. Blasiak J, et al. Zinc and Autophagy in Age-Related Macular Degeneration. Int J Mol Sci. 2020 Jul; 21(14): 4994.
  2. Sperduto R D, et al. The Linxian cataract studies. Two nutrition intervention trials. Arch Ophthalmol. 1993 Sep;111(9):1246-53.

Selenium is essential for the enzymatic reaction responsible for the synthesis of glutathione, a powerful physiological molecule which constantly protects the body from oxidative damage. A lack of selenium will thus result in a loss of the detoxification capacity of the body, immuno-depression and onset of degenerative diseases such as cancer.

Selenium, a mineral and antioxidant found naturally in foods like Brazil nuts, can reduce the risk of developing macular degeneration and act as a strong antioxidant for eye protection.(1) Selenium, when combined with Melatonin, also may help decrease levels of toxic MDA while significantly increasing levels of the powerful antioxidant Glutathione.(2)

  1. Hock Eng Khoo, Hui Suan Ng, et al. Nutrients for Prevention of Macular Degeneration and Eye-Related Diseases. Antioxidants (Basel). 2019 Apr; 8(4): 85.
  2. Hande Hüsniye Telek. Effects of Selenium and Melatonin on Ocular Ischemic Syndrome. Biomed Res Int. 2019; 2019: 8080564.

Note: ARMeD™ should not be taken during pregnancy or while nursing. Alcohol, NSAIDS (anti-inflammatory medications) or beta-blockers may inhibit the benefits of Melatonin.